NT5EMutations and Arterial Calcifications

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Arterial calcifications

Arterial calcifications as found with various imaging techniques, like plain X-ray, computed tomography or ultrasound are associated with increased cardiovascular risk. The prevalence of arterial calcification increases with age and is stimulated by several common cardiovascular risk factors. In this review, the clinical importance of arterial calcification and the currently known proteins invo...

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NT5E mutations and arterial calcifications.

BACKGROUND Arterial calcifications are associated with increased cardiovascular risk, but the genetic basis of this association is unclear. METHODS We performed clinical, radiographic, and genetic studies in three families with symptomatic arterial calcifications. Single-nucleotide-polymorphism analysis, targeted gene sequencing, quantitative polymerase-chain-reaction assays, Western blotting...

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Vascular calcifications, arterial aging and arterial remodeling in ESRD.

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Association between arterial calcifications and nonlacunar and lacunar ischemic strokes.

BACKGROUND AND PURPOSE Nonlacunar cerebral infarcts are presumed to be caused by thromboembolism from the heart or extracranial arteries, whereas lacunar infarcts are thought to be caused by small vessel disease. We investigated to what extent arterial calcifications differ between nonlacunar and lacunar ischemic strokes. METHODS We studied 820 consecutive patients with transient ischemic att...

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Arterial calcifications and bone histomorphometry in end-stage renal disease.

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2011

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmoa0912923